A Polyherbal Mixture with Nutraceutical Properties for Ruminants: A Meta-Analysis and Review of BioCholine Powder.

BioCholine Powder is a polyherbal feed additive composed of Achyrantes aspera, Trachyspermum ammi, Azadirachta indica, and Citrullus colocynthis. The objective of this study was to analyze published results that support the hypothesis that the polyherbal product BioCholine Powder has rumen bypass choline metabolites through a meta-analysis and effect size analysis (ES). Using Scopus, Web of Science, ScienceDirect, PubMed, and university dissertation databases, a systematic search was conducted for experiments published in scientific documents that evaluated the effects of BioCholine supplementation on the variables of interest. The analyzed data were extracted from twenty-one publications (fifteen scientific articles, three abstracts, and three graduate dissertations available in institutional libraries). The studies included lamb growing-finishing, lactating ewes and goats, calves, and dairy cows. The effects of BioCholine were analyzed using random effects statistical models to compare the weighted mean difference (WMD) between BioCholine-supplemented ruminants and controls (no BioCholine). Heterogeneity was explored, and three subgroup analyses were performed for doses [(4 (or 5 g/d), 8 (10 g/d)], supplementation in gestating and lactating ewes (pre- and postpartum supplementation), and blood metabolites by species and physiological state (lactating goats, calves, lambs, ewes). Supplementation with BioCholine in sheep increased the average daily lamb gain (p < 0.05), final body weight (p < 0.01), and daily milk yield (p < 0.05) without effects on intake or feed conversion. Milk yield was improved in small ruminants with BioCholine prepartum supplementation (p < 0.10). BioCholine supplementation decreased blood urea (p < 0.01) and increased levels of the liver enzymes alanine transaminase (ALT; p < 0.10) and albumin (p < 0.001). BioCholine doses over 8 g/d increased blood glucose, albumin (p < 0.10), cholesterol, total protein, and globulin (p < 0.05). The ES values of BioCholine in retained energy over the control in growing lambs were +7.15% NEm (p < 0.10) and +9.25% NEg (p < 0.10). In conclusion, adding BioCholine Powder to domestic ruminants' diets improves productive performance, blood metabolite indicators of protein metabolism, and liver health, showing its nutraceutical properties where phosphatidylcholine prevails as an alternative that can meet the choline requirements in ruminants.

Evidence of good and bad player momentum between games in basketball / Evidencia de buen y mal momentum entre partidos para el jugador de baloncesto / Evidência de bom e mau momentum entre os jogos para o jogador de basquete

La existencia de rachas en baloncesto ha sido estudiada en equipos (momentum del equipo) y jugadores (mano caliente/momentum del jugador), utilizando diferentes métodos y alcanzando resultados contradictorios. Sin embargo, investigación empírica reciente muestra que este tipo de fenómenos de rachas son reales y no un sesgo de la percepción. En esta investigación se analiza una forma de rachas de juego para el jugador que hasta ahora no había sido considerada: el momentum del jugador entre partidos. Empleando una muestra de 39 jugadores y 3483 partidos de las temporadas 2016/17 y 2017/18 en la NBA, se analiza los puntos anotados por minuto en situaciones de muy alto y también muy bajo rendimiento. Los resultados sugieren que hay una cierta tendencia que refleja el momentum, tanto para buenos como para malos rendimientos, pero ese resultado está influenciado por el porcentaje de uso del jugador, es decir, su capacidad para acaparar juego. La tendencia es ir hacia atrás (en torno a un 60-70%) en ladistribución de anotaciones tras un partido muy bueno, y de ir hacia delante (en torno a un 30-40%) en la distribución de anotaciones tras un partido muy malo. Las implicaciones para la toma de decisiones son discutidas finalmente.(AU)

The existence of streaks in basketball has been studied for teams (team momentum) and players (hot hand/player momentum) using disparate methods and reaching some conflicting results. However, recent empirical research shows these types of streaks are real and not an artifact of perception. In this research, we analyze a form of player streak that has not been considered before player momentum between games. Using a sample of 39 players and 3483 games of the 2016/17 and 2017/18 NBA regular seasons, we studied the distribution of points scored per minute focusing on both tails of this distribution for each player, i.e., extremely high, and extremely low performance within the same season. Results suggest that there is a certain trend reflecting momentum (for both good and bad performances), but this outcome is influenced by the usage percentage. The trend is to jump back to around 60-70% of the distribution of scores after a very good game and to jump forward to around 30-40% of the distribution of scores after a very bad game. Implications for decision-making are discussed at the end.(AU)

A existência de sequências no basquetebol têm sido estudadas em equipas (momentum da equipa) e jogadores (mão quente/momentum do jogador), utilizando diferentes métodos e chegando a resultados contraditórios. No entanto, estudosempíricos recentes evidenciaram queesse tipo de fenômeno é real e não um viés de percepção. Este estudo analisou uma forma de sequência de jogo para o jogador que até então não havia sido considerada: o ímpeto do jogador entre as partidas. Para tal, participaram neste estudo 39 jogadores e 3483 jogos das temporadas 2016/17 e 2017/18 da NBA, e foram analisados os pontos marcados por minuto em situações de alto e baixo desempenho. Os resultados sugerem que existe uma certa tendência que reflete o momentum, tanto para as boas como para as más exibições, mas esse resultado é influenciado pela percentagem de aproveitamento do jogador, ou seja, a sua capacidadede dominaro jogo. As implicações para a tomada de decisão são finalmente discutidas.(AU)

Effect of the Supplementation Using an Herbal Mixture as a Choline Source during Early Gestation in Rambouillet Ewes.

Previous research indicates that adequate choline nutrition during late gestation improves fetal development. However, there is a lack of studies describing choline's role during early gestation. Thus, the current study hypothesizes that an herbal mixture as a source of choline (Biocholine) positively affects offspring development from ewes supplemented during early gestation. Therefore, the objectives were to evaluate the impact of biocholine on the programming of the offspring early in life through the evaluation of dams and newborn performance. Twenty-eight four-year-old Rambouillet ewes were assigned randomly to two treatments: non-supplementation and 4 gd-1 of biocholine during the early gestation. Compared with the dams without supplementation, the ewes supplemented using biocholine showed no increase in parameters such as birth and weaning weight (p > 0.05). Additionally, the milk yield and quality of colostrum and milk did not present statistical differences (p > 0.05). However, the placental membrane development was reduced in the ewes that received supplementation with biocholine; interestingly, those dams increased the weight of the newborns during the lambing period (p < 0.05). Finally, the current study proposes necessary elucidation of how placental size is programmed and if less placental development has potential benefits in the fetus's development.

Influence of a Polyherbal Choline Source in Dogs: Body Weight Changes, Blood Metabolites, and Gene Expression.

Choline chloride is used to provide choline in dog foods; however, in other domestic species, it has been replaced with a polyherbal containing phosphatidylcholine. A polyherbal containing Achyrantes aspera, Trachyspermum ammi, Citrullus colocynthis, Andrographis paniculata, and Azadirachta indica was evaluated in adult dogs through body weight changes, subcutaneous fat thickness, blood metabolites, and gene expression. Forty dogs (4.6 ± 1.6 years old) who were individually housed in concrete kennels were randomly assigned to the following treatments: unsupplemented diet (377 mg choline/kg), choline chloride (3850 mg/kg equivalent to 2000 mg choline/kg diet), and polyherbal (200, 400, and 800 mg/kg) for 60 days. Blood samples were collected on day 59 for biochemistry, biometry, and gene expression analysis through microarray assays. Intake, final body weight, and weight changes were similar for the two choline sources. Feed intake variation among dogs (p = 0.01) and dorsal fat (p = 0.03) showed a quadratic response to herbal choline. Dogs that received the polyherbal diet had reduced blood cholesterol levels (Quadratic, p = 0.02). The gene ontology analysis indicated that 15 biological processes were modified (p ≤ 0.05) with implications for preventing cardiovascular and metabolic diseases, cancer prevention, inflammatory and immune response, and behavior and cognitive process. According to these results that were observed in a 60 day trial, the polyherbal form could replace choline chloride in dog diets at a concentration of 400 mg/kg.

[Prevalence of depression, anxiety, and associated factors in residents from hospital centers during COVID-19 pandemic]. / Prevalencia de depresión, ansiedad y factores asociados en médicos residentes de centros hospitalarios durante la pandemia de COVID-19.

OBJECTIVE: To determine anxiety and depression frequency in residents from hospital centers during COVID-19 pandemic. METHODS: A descriptive, observational, cross-sectional study was carried out from June to December 2020. Residents from hospitals of Secretary of Health, Puebla, were identified. The sample included 247 residents, who had an individual interview and answered a questionnaire through CEMEVI (Virtual Medical Center of High Specialty). RESULTS: 17 % of anxiety and 45 % of depression were reported. The most frequent age group was 26 to 31 years; 124 women and 123 men; anesthesiology, internal medicine and pediatrics were the medical specialties with greater depression; internal medicine and pediatrics were the medical specialties with greater anxiety. The risk factors for depression were anxiety (OR = 36.9), record of contact with COVID-19 patients (OR = 2.49 p = 0.035), and parental anxiety record (OR = 2.6, p = 0.009). The medical history of parents with anxiety was risk factor for anxiety (OR = 2.3, p = 0.031). CONCLUSIONS: Prevalence of depression and anxiety should alert to seek answers to the problem.

OBJECTIVO: Determinar la frecuencia de ansiedad y depresión en médicos residentes en centros hospitalarios en México durante la pandemia de COVID-19. MÉTODOS: Se realizó estudio transversal observacional de junio a diciembre de 2020. Se identificaron médicos residentes de diferentes hospitales de la Secretaría de Salud en Puebla. La muestra incluyó a 247 médicos residentes, quienes fueron entrevistados individualmente y a través de un cuestionario de CEMEVI (Centro Médico Virtual de Alta Especialidad). RESULTADOS: La frecuencia de ansiedad fue de 17 % y de depresión, de 45 %. El grupo etario más frecuente fue el de 26 a 31 años: 124 médicos fueron mujeres y 123 hombres; los médicos de las especialidades que mostraron mayor frecuencia de depresión fueron anestesiología, medicina interna y pediatría; y de ansiedad, medicina interna y pediatría. Los factores de riesgo para depresión fueron ansiedad (RM = 36.9), historia de contacto con paciente con COVID-19 (RM = 2.49, p = 0.035) e historia de ansiedad en los padres (RM = 2.6, p = 0.009). La ansiedad se asoció con historia de padres con este trastorno (RM = 2.3, p = 0.031). CONCLUSIONES: La frecuencia de depresión y ansiedad en la población de médicos residentes debe alertar a buscar respuestas al problema.

La consideración de la propagación de errores en el análisis de importancia-valoración en gestión deportiva / The consideration of the propagation of errors for the importance-performance analysis in sports management / A consideração da propagação de erros na análise importância-desempenho em gestão esportiva

El análisis de importancia-valoración es una herramienta cada vez más empleada en la gestión de servicios deportivos, pero necesita ser enfocado desde una perspectiva más completa a la hora de calcular y reportar los errores de medición. En esta investigación hemos dado las indicaciones precisas para ayudar a mejorar esta situación, fundamentalmente a través del cálculo de las barras de error y la propagación de errores para cualquier función que se construya empleando las variables originales: importancia y valoración. A través de la simulación de varias distribuciones de probabilidad hemos calculado la imprecisión en las estimaciones, desarrollando la aproximación de Taylor para computar la varianza de una función de las variables originales. Las implicaciones para la investigación y gestión deportiva son discutidas finalmente

The importance-performance analysis (IPA) is a tool increasingly used in the management of sports services, but needs to be implemented from a more complete perspective when calculating and reporting measurement errors. In this research, we have provided precise indications to help to get that aim, through the calculation of the error bars and the propagation of errors for any function of the original variables: importance and performance. Through the simulation of several probability distributions, we have calculated the imprecision in the estimates, developing the Taylor approximation to compute the variance of a function of the original variables. The implications for sports research and management are finally discussed

A análise importância-desempenho é uma ferramenta cada vez mais utilizada no gerenciamento de serviços esportivos, mas precisa ser focada a partir de uma perspectiva mais completa ao calcular e relatar erros de medição. Nesta investigação, damos as indicações precisas para ajudar a melhorar esta situação, fundamentalmente através do cálculo das barras de erro e a propagação de erros para qualquer função que é construída usando as variáveis originais: importância e desempenho. Através da simulação de várias distribuições de probabilidade, calculamos a imprecisão nas estimativas, desenvolvendo a aproximação de Taylor para calcular a variância de uma função das variáveis originais. As implicações para a pesquisa e gestão esportiva são finalmente discutidas

La medición de la satisfacción del consumidor de servicios deportivos a través de la lógica borrosa / Customer satisfactionwith sports services: a fuzzy logic approach

esta investigación plantea el problema de medir la satisfacción de los consumidores de servicios deportivos desde un enfoque novedoso en psicología del deporte: la modelización de la incertidumbre a través del uso de la lógica borrosa. se han descrito sencillos procedimientos de análisis para operar con técnicas borrosas, con el fin de comprobar empíricamente en qué medida esta metodología puede complementar los resultados derivados de los métodos estadísticos tradicionales. de este modo, se profundiza sobre la relación entre las evaluaciones numéricas de la satisfacción de los consumidores y el grado de incertidumbre asociado a las evaluaciones lingüísticas. el enfoque propuesto ofrece la posibilidad de obtener información más rica sobre las actitudes del consumidor de servicios deportivos, superando las desventajas de los enfoques en “tercera persona” y evitando la posibilidad de la aparición de sesgo por categorización y por interacción entre juicios verbales y numéricos (AU)

This study focuses on measuring customer satisfaction within the context of sports services by using a novel approach in sport psychology: modelling uncertainty through the application of fuzzy logic. several analytical procedures for dealing with fuzziness have been described in order to verify empirically the extent to which this methodology complements the traditional statistical approach. this study examines the relationships between numerical evaluations of customer satisfaction and the degree of uncertainty linked to these verbal judgements. the proposed approach enriches the information on the attitudes of sport service consumers and overcomes the shortcomings of the “third-person” perspective. In addition, this proposal is robust against two sources of bias: scale coarseness, and interaction between numerical and verbal judgements (AU)

2El análisis factorial confirmatorio y la validez de escalas en modelos causales / Confirmatory factor analysis and the validity of the measurement scales within a causal modelling framework

Este artículo discute el papel que juegan los modelos de ecuaciones estructurales, y más concretamente, el análisis factorial confirmatorio, en relación a la validez de las escalas de medida cuando se proponen modelos causales. Se discuten los postulados de Hayduk (1996) y Borsboom, Mellenbergh y van Heerden (2004), con el fin de proveer un marco de análisis sobre el que los investigadores puedan decidir cómo operar a nivel empírico. El contraste de estas visiones en relación a la utilización generalizada del análisis en dos pasos de Anderson y Gerbing (1988), debe estimular la reflexión acerca de la idoneidad de éste último, y de los análisis de correlaciones asociados a la validez de criterio, convergente y discriminante(AU)

This research discusses the role of structural equation models and, specifically, confirmatory factor analysis, regarding the validity of the measurement scales when a casual model is proposed. The viewpoints of Hayduk (1996) and Borsboom, Mellenbergh and van Heerden (2004) are discussed, in order to provide a framework upon which researchers can decide how to proceed in applied research. The divergences of these perspectives with regard to the widespread use of the twostep procedure (Anderson and Gerbing, 1988) should encourage thinking about the suitability of the confirmatory factor analysis, and the adequacy of the empirical procedures for studying criterion, convergent and discriminant validity(AU)

La validez discriminante como criterio de evaluación de escalas: ¿teoría o estadística? / Discriminant validity as a scale evaluation criterion: theory or statistics?

La validez discriminante es uno de los criterios habituales para evaluar las escalas de medida de constructos latentes en ciencias sociales. Este artículo muestra como se pueden obtener resultados contradictorios si se aplican diferentes procedimientos estadísticos, por lo que se recomienda evaluar de forma teórica la divergencia entre escalas que representan conceptos. De este modo, la validez de contenido actúa como criterio robusto frente a determinados análisis estadísticos basados en covarianzas.

Discriminant validity is one of the usual criteria for evaluating measurementscales that define latent constructs in social sciences. This article shows howdifferent statistical procedures frequently used for accomplishing this aim can yield misleading results. Authors recommend a theoretical judgement about divergence among scales that are manifestation of latent concepts. Therefore, content validity represents a robust condition against certain covariance statistical based analysis.

Use of Pleurotus Pulmonarius to change the nutritional quality of wheat straw. I: Effect on chemical composition / Uso de Pleurotus Pulmonarius para cambiar la calidad nutritiva de la paja de trigo. I: Efecto en la composición química / Uso de Pleurotus Pulmonarius para mudar a qualidade nutritiva da palha de trigo. I: Efeito na composição química

The effect of Pleurotus pulmonarius on the chemical composition of wheat straw was evaluated. Wheat straw, treated and untreated with P. pulmonarius, was obtained from a commercial facility. Ten samples plastic bags of wheat straw used previously as substrate to culture edible fungus were collected at random. The negative control group consisted of the pasteurized wheat straw untreated with P. pulmonarius. All samples were analyzed to determine dry matter, organic matter, crude protein, neutral detergent fiber, acid detergent fiber, cellulose and hemicellulose of each wheat straw. Data were analyzed by mean comparison using a t-Student test. No differences (P>0.05) between treatments were found for dry matter, crude protein and hemicellulose; however, straw treated with P. pulmonarius showed higher percentages (P<0.05) of organic matter, neutral and acid detergent fiber. It is concluded that growing P. pulmonarius in wheat straw improves the chemical composition of the straw by increasing its organic matter content and modifies the fiber structure, which increases the soluble carbohydrates content.

Se midió el efecto en la composición química de la paja de trigo usada como sustrato en la producción de Pleurotus pulmonarius. Las pajas de trigo, tanto tratadas con P. pulmonarius como no tratadas, fueron obtenidas de una empresa comercial. Para obtener muestras representativas para el análisis químico se tomaron al azar diez bolsas de la paja usada como sustrato para cultivar el hongo. El grupo testigo consistió en las pajas esterilizadas sin tratamiento con P. pulmonarius. A todas las muestras se les determinó materia seca, materia orgánica, proteína cruda, fibra detergente neutro, fibra ácido detergente, celulosa y hemicelulosa. Los datos obtenidos fueron analizados mediante una comparación de medias utilizando una prueba de t-Student. No se encontraron diferencias (P>0,05) para el porcentaje de materia seca, proteína cruda y hemicelulosa; sin embargo, se presentó un mayor (P<0,05) porcentaje de materia orgánica, fibra detergente neutro y ácido para la paja tratada en comparación con la no tratada. Se concluye que el crecimiento del P. pulmonarius en paja de trigo mejora la composición química de las pajas aumentando el contenido de materia orgánica y modifica la estructura de la fibra, con lo que se incrementa el contenido de carbohidratos solubles.

Mede-se o efeito na composição química da palha de trigo usada como substrato na produção de Pleurotus pulmonarius. As palhas de trigo, tanto tratadas com P. pulmonarius como não tratadas, foram obtidas de uma empresa comercial. Para obter amostras representativas para a análise química se tomaram aleatoriamente dez sacolas da palha usada como substrato para cultivar o fungo. O grupo testemunha consistiu em palhas esterilizadas sem tratamento com P. pulmonarius. Determinou-se, em todas as amostras, matéria seca, matéria orgânica, proteína crua, fibra detergente neutro, fibra ácido detergente, celulose e hemicelulose. Os dados obtidos foram analisados mediante uma comparação de médias utilizando uma prova de t. Não se encontraram diferenças (P>0,05) para a porcentagem de matéria seca, proteína crua e hemicelulose; no entanto, se apresentou uma maior (P<0,05) porcentagem de matéria orgânica, fibra detergente neutra e ácida para a palha tratada em comparação com a não tratada. Conclui-se que o crescimento do P. pulmonarius na palha de trigo melhora a composição química das palhas aumentando o conteúdo de matéria orgânica e modifica a estrutura da fibra, com o que se incrementa o conteúdo de carboidratos solúveis.

Determinación de la máxima varianza para el cálculo del factor de imprecisión sobre la escala de medida, y extensión a diferentes tipos de muestreo / Determining the most unfavourable variance to calculate the Measurement Scale Imprecision Factor, and extension to other types of sampling methods

La precisión de las estimaciones tiene que ser adecuadamente descrita en la investigación mediante encuesta, donde las escalas de medida ordinales y de intervalo son comúnmente utilizadas. En relación a la estimación de valores medios poblacionales, los errores absoluto y relativo están en función de esas escalas de medida. Este trabajo discute algunas de las asunciones en las que se fundamenta el «Factor de Imprecisión sobre la Escala de Medida -FIEM-». Este índice es una herramienta para evaluar el grado de imprecisión de las estimaciones, independientemente del rango de la escala de medida considerado. Específicamente, proponemos un nuevo método para determinar la varianza más desfavorable, el cual es consistente con la asunción de normalidad en la población, a diferencia del método original basado en una distribución bimodal. Este método reduce el valor de la varianza más desfavorable, y es fácilmente calculado a partir de la función de distribución normal estándar. Además, se muestra la relación de FIEM con otros tipos de muestreo probabilístico, como el muestreo estratificado y por conglomerados (AU)

The precision of estimates must be adequately reported in survey research, where ordinal and interval measurement scales are commonly used. Regarding mean estimate, absolute and relative errors exist as a function of the measurement scales. This manuscript discusses some assumptions underlying the development of the Measurement Scale Imprecision Factor -MSIF-, a tool to assess the degree of imprecision of estimates, regardless of the scale rank considered. Specifically, we propose a new method for determining the most unfavourable variance, which is consistent with the normal distribution assumption, unlike the original assumption based on the bimodal distribution. This method reduces the value of the most unfavourable variance, which is easily computed using the cumulative normal standard distribution function. In addition, we show the relationship between MSIF and other types of probabilistic sampling methods, such as stratified and cluster sampling (AU)

[Determining the most unfavourable variance to calculate the Measurement Scale Imprecision Factor, and extension to other types of sampling methods]. / Determinación de la máxima varianza para el cálculo del factor de imprecisión sobre la escala de medida, y extensión a diferentes tipos de muestreo.

The precision of estimates must be adequately reported in survey research, where ordinal and interval measurement scales are commonly used. Regarding mean estimate, absolute and relative errors exist as a function of the measurement scales. This manuscript discusses some assumptions underlying the development of the Measurement Scale Imprecision Factor--MSIF--, a tool to assess the degree of imprecision of estimates, regardless of the scale rank considered. Specifically, we propose a new method for determining the most unfavourable variance, which is consistent with the normal distribution assumption, unlike the original assumption based on the bimodal distribution. This method reduces the value of the most unfavourable variance, which is easily computed using the cumulative normal standard distribution function. In addition, we show the relationship between MSIF and other types of probabilistic sampling methods, such as stratified and cluster sampling.

[Prevention of thromboembolism in patients with chronic atrial fibrillation in primary health care]. / Prevención de la enfermedad tromboembólica en pacientes con fibrilación auricular crónica en atención primaria.

BACKGROUND AND OBJECTIVE: Our goal was to evaluate the appropriateness of antithrombotic treatment administration in patients with chronic atrial fibrillation (CAF) attended in a health primary center. PATIENTS AND METHOD: Transverse and descriptive study; 416 patients diagnosed with CAF were included out of a population of 28,447. Age, sex, embolism risk factors, antithrombotic therapy, contraindications to anticoagulation and stratification risk variables were collected. After a bivariate analysis, a logistic regression model was done to analyze the variable associated with an incorrect antithrombotic therapy. RESULTS: 81% patients were given a correct antithrombotic therapy: 96.8% with a valvular-CAF pattern and 78.2% with a non-valvular CAF pattern. Older the patient, higher the percentage of incorrect antithrombotic administration (t = 3.184; p = 0.002). A greater embolic risk was associated with a better antithrombotic treatment (p < 0.001). The existence of at least one risk factor was also associated with a correct administration (p < 0.001). Hypertension, mitral valvular heart disease and valvular prosthesis were factors associated with a correct antithrombotic therapy. In a multivariate analysis, limited quality of life, mitral valvular heart disease, hypertension and previous systemic embolism behaved all as protective factors of a wrong treatment. An age older than 80 years was associated with a risk of treatment which was 2.89 times higher than that of individuals with the same age or youngers (OR = 2.89; 95% CI, 1.68-4.95). CONCLUSIONS: Most patients with CAF, both valvular and non-valvular, were properly given antithrombotic therapy. The main factor associated with an incorrect antithrombotic therapy was advanced age.

Prevención de la enfermedad tromboembólica en pacientes con fibrilación auricular crónica en atención primaria / Prevention of thromboembolism in patients witth chronic atrial fibrillation in primary health care

FUNDAMENTO Y OBJETIVO: Evaluar si los pacientes con fibrilación auricular crónica atendidos en un centro de salud siguen un tratamiento antitrombótico correcto. PACIENTES Y MÉTODO: Estudio descriptivo transversal, en el que se incluyó a 416 pacientes diagnosticados de fibrilación auricular crónica, de una población de 28.847 pacientes. Se recogieron las siguientes variables: edad, sexo, factores de riesgo embolígeno, tratamiento antitrombótico pautado, condicionantes y contraindicaciones para la anticoagulación, tratamiento antitrombótico correcto o no y estratificación del riesgo. Tras un análisis bivariante, realizamos un modelo de regresión logística para analizar las variables asociadas a un riesgo de mal tratamiento. RESULTADOS: El 81 por ciento recibía tratamiento antitrombótico correcto, un 96,8 por ciento se hallaba en fibrilación auricular valvular y un 78,2 por ciento, en no valvular. A mayor edad, el porcentaje de pacientes con mal tratamiento antitrombótico fue mayor (t = 3,184; p = 0,002). Un mayor riesgo embolígeno se asoció a mejor tratamiento antitrombótico (p < 0,001). La existencia de al menos un factor de riesgo se asoció a un tratamiento correcto (p < 0,001). Entre los factores de riesgo, sólo la hipertensión arterial, la valvulopatía mitral y la presencia de prótesis valvular tenían significación estadística. En el análisis multivariante, la calidad de vida limitada (odds ratio [OR] = 0,13; intervalo de confianza [IC] del 95 por ciento, 0,02-0,59), la existencia de valvulopatía mitral (OR = 0,13; IC del 95 por ciento, 0,03-0,57), la hipertensión arterial (OR = 0,36; IC del 95 por ciento, 0,20-0,63) y el antecedente de embolia sistémica (OR = 0,41; IC del 95 por ciento, 0,17-0,99) se comportaron como factores protectores de un mal tratamiento. La edad superior a 80 años se asoció a un riesgo de mal tratamiento 2,89 veces mayor que el de las personas de esa edad o menores (OR = 2,89; IC del 95 por ciento, 1,68-4,95). CONCLUSIONES: En nuestro centro, la mayoría de los pacientes con fibrilación auricular crónica, valvular y no valvular, reciben un tratamiento antitrombótico correcto, y la edad es el factor que más se asocia a un mal tratamiento (AU)